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Zhang, Y., Gaetano, C

tricolor were harvested at 55 DAS

Although several candidate drug resistance mechanisms, including impaired DNA repair, decreased drug uptake, increased drug efflux and detoxification, have been proposed (reviewed by Galluzzi et al, 2012), we are still some way from understanding the molecular basis of drug resistance, and from developing biomarkers to predict the onset and monitor the development of drug-resistant disease in cancer patients

However, these same active ingredients can also induce neurotoxicity and autonomic dysfunction, with overdose leading to such adverse effects

an anthracycline such as aclarubicin, daunorubicin, doxorubicin, epirubicin, idarubicin, amrubicin, pirarubicin, valrubicin, or zorubicin an anthracenedione such as mitoxantrone, or pixantrone an anti-tumor antibiotic isolated from Streptomyces such as actinomycin the therapeutic agents may be formulated and/or administered with additional active agents such as one or more biological agents