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these conditions generally result from the blockage (embolism) or rupture (hemorrhage) of blood vessels, ultimately leading to stroke (ischemic or hemorrhagic, respectively) ( As the brain is susceptible to OS, increasing amounts of ROS/RNS, impaired oxidants/antioxidant systems, and mitochondrial dysfunction together initiate neurodegenerative processes

(A) The effect of sh-GSTP1 on GSTP1 protein expression using Western blot

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4.3 Neuroglobin (NGB) Discovered in neurons, NGB is a stress-inducible globin with strong antioxidant and anti-apoptotic actions

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