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Increased Hunger: Elevated GH and IGF-1 levels can ramp up appetite, which might be a downside for those focused on fat loss

Multiple studies have been conducted connecting deficiencies in these hormones to the length of lifespan and how different variables such as diet can further affect an animals lifespan

The activated STAT proteins may then translocate to the nucleus, where they might bind to specific DNA sequences called response elements, possibly leading to the transcription of the IGF-I gene

reducing it improves the metabolic environment even as GH's acute effects on glucose metabolism work in the opposite direction

Regardless, the aforementioned research by Ng et al

mnben87 September 17, 2020, 9:11pm 25 I havent tested without AI yet (but AI dose was pretty low)