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In addition, they have shown reproducible efficacy in vivo and have progressed into evaluation through clinically relevant delivery systems , including ethosomes, nanoemulsions, and nanogels [37, 39]

Exogenous sources of free radicals include environmental factors such as ultraviolet (UV) radiation, ionizing radiation, tobacco smoke, pollution, and exposure to certain chemicals and drugs [24]

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Currently, methods used are constrained by long measurement run times and suffer from issues- relating to the fragility of high-temperature metal oxide reactors used to convert steroids toCO2 for CIR in conventional GCC-IRMS instrumentation