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Cell Cycle (2010) 9(17):3485505

Drug library screening identified several promising radioprotective compounds The glutathione and senescence assays were used to screen a library of FDA-approved drugs (Selleck Chemicals) at 100 M

In the reviewed studies, the effect of WS on immune markers depended on the animal model used

Subcutaneous injection means the dose is delivered just under the skin with a fine needle, a route commonly used for peptide protocols because it allows steady, self-managed dosing

Clinical response rates in clinical trials have ranged from 30 to 60% over the first eight to 12 weeks, with endoscopic remission usually slower in onset

Knock-out of IGF-1 in the liver alone results in relatively normal sized mice with a 75% reduction in circulating IGF-1 levels, suggesting that local IGF-1 may be more important for body growth than liver IGF-1 [18]