interaction of chloroacetamide electrophiles with cellular glutathion General concept unsaturated PV‐electrophiles in Cys‐selective Advances in covalent drug discovery

Advances in covalent drug discovery Nature Reviews Drug Discovery Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S Transferase Pi 1 Inhibition by the Anti cancer Compound Piperlongumine* Journal of Biological Chemistry New mechanistic insights into halogen dependent cytotoxic pattern of monohaloacetamide disinfection byproducts ScienceDirect Design, synthesis, and biological evaluation of nitroisoxazole containing spiro[pyrrolidin oxindole] derivatives as novel glutathione peroxidase 4 mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation ScienceDirect Glutathione Dynamics in Subcellular Compartments and Implications for Drug Development PMC Expanding the Chemistry of Dihaloacetamides as Tunable Electrophiles for Reversible Covalent Targeting of Cysteines Journal of Medicinal Chemistry

SKU: 67904973303 · From eiffelbuilders.com