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A substantial proportion of patients treated with semaglutide achieved clinically significant weight loss thresholds (5%, 10%, 15%), with these benefits appearing to be maintained over time, as indicated by data from the SUSTAIN 5 trial [62], which employed a different drug (PHEN/TPM CR)

LPS administration induced significant phosphorylation of NF-B p65 (Ser536), p38 MAPK, and JNK1/2 in lung homogenates

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