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This study also showed that levels of choline intake were inversely associated with homocysteine concentrations in the blood

Long-term LC supplementation has been shown to elevate fasting plasma TMAO levels, raising concerns about its implications for cardiovascular health, despite its potential benefits in improving muscle mass and physical performance

Clin Endocrinol (Oxf) 2014;80(3):425-31

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From pharmaceuticals to nutraceuticals: Bridging disease prevention and management