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Like conventional pulse oximetry, increased methemoglobin fractions lead to falsely decreased SpO 2 measurements that underestimate the true SaO 2 [1, 9]

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It also helps in maintaining the integrity of the DNA, which is essential for cellular regeneration

Pupil responses are known to be a faithful indirect indicator of activity in the locus coeruleus in mice, even though also the cholinergic neuromodulatory system plays a role for sustained pupil dilation (Reimer et al

For deeper compound-specific guides, see the PT-141 protocol and the afamelanotide protocol