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Too much sugar in the blood may exhaust liver function

2008;3:e2459

High-dose protocols (1.52mg daily) push toward the upper threshold where copper ion accumulation becomes a concern

Specifically, naringin increased the expression of BDNF, its receptor TrkB, and phosphorylated CREB, while simultaneously reducing COX-2 and Bax expression (Choi et al., 2023)