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The disease is also more common among people older than age 60

Glutathione acts as a direct antioxidant

Importantly, lifestyle-associated exposures modulate the biosynthesis of inflammatory mediators and enhance the generation of ROS, thereby amplifying the inflammatory response

Cur plays a role in bone resorption by blocking the differentiation of osteoclast precursors into osteoclasts by inhibiting the production of the chemokine CCL3