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and iii) increased oxidative stress, due to the putative role of thiamine in prostaglandin expression, decreased lipid peroxidation as well as expression of nitric oxide synthase (143, 144), and its involvement as a cofactor for TKT in the PPP, master regulator of NADPH homeostasis

Artesunate attenuates skin hypertrophic scar formation by inhibiting fibroblast activation and EndMT of vascular endothelial cells

The carrageenan-induced increase in the levels of the cytokine-inducible nitric oxide synthase, IL-1, and IL-6 was abrogated following treatment with CBC

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Clinical manifestations include negative symptoms, such as affective flattening, social disengagement, and avolition, as well as positive symptoms, including hallucinations and delusions