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Renal and Hepatic Impairment Dosage: Although the safety and efficacy of hydroxocobalamin have not been studied in renal and hepatic impairments, Cyanokit is administered as emergency therapy in an acute, life-threatening situation only and no dose adjustment is required in these patients

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WADA clarified the prohibited status of AOD-9604 in 2013 following its mention in the Australian Football League supplements investigation, and the substance has remained named on the list in every subsequent annual revision