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Garland SN, Valentine D, Desai K, Li S, Langer C, et al

Han Y, Chaouch S, Mhamdi A, Queval G, Zechmann B, Noctor G (2013) Functional analysis of Arabidopsis mutants points to novel roles for glutathione in coupling H 2 O 2 to activation of salicylic acid accumulation and signaling

Consequently, the membrane localization of xCT and its cysteine transport function for GSH synthesis are enhanced, cooperatively generating anti-ferroptosis effects in carbon tetrachloride-induced rat ALI model and H2O2-induced liver cell injury model (89)

TrxR2, which is exclusively expressed in mitochondria

1 Introduction Excessive alcohol consumption is a major global health concern, responsible for an estimated 4 -cell dysfunction and apoptosis through glucokinase nitration and its down-regulation

The overexpressed GSH in cancer cells would degrade the framework of Fe(II)-BNCP, and trigger rapid NO liberation in situ , thereby leading to synergistic NO-CDT effect for the retardation of tumor growth