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Study 4 evaluated neuronal activation in response to acute treatment with Cagrilintide or sCT in WT, RAMP1 KO, RAMP3 KO, and RAMP1/3 KO mice

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To further confirm that GSTM2 is a downstream target for YTHDF1, we overexpressed GSTM2 in YTHDF1 KO cells (Fig

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124,125 Oxidation induces conformational changes, enhancing dissociation rates, particularly in the C-terminus of Ku80, which contains Cys493 and Cys638 and is crucial for DNA-PKcs recruitment