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Current Opinion in Endocrine and Metabolic Research, 22, 100417

This prevents its degradation, enhances cell-matrix adhesion, and activates focal adhesion kinase (FAK)/SRC signaling pathways, thereby driving tumor metastasis ( 3.2 Viral proteins as substrate receptors: hijacking CUL5 for immune evasion and tumorigenesis To evade host immune surveillance or facilitate their own replication, numerous viruses have evolved proteins capable of hijacking the host CRL5 system

The hepatic conversion of vitamin D 3 to 25(OH)D 3 occurs in microsomal and mitochondrial compartments and is catalyzed by vitamin D 3 -25-hydroxylase

Cancer 70 MorbidelliL.DonniniS.FilippiS.MessoriL.PiccioliF.OrioliP.et al (2003)

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Novel roles for glutathione in gene expression, cell death, and membrane transport of organic solutes