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Ethics declarations Competing Interests X.F., S.A.C., J.A.L., J.C., B.A.K

IACS-16898 showed an AUC of 802 hr * M (Supplementary Table S10) and low in vivo clearance of 4 mL/min/kg, with a half-life of 4 h in mice (Supplementary Table S11), making it suitable for in vivo therapeutic use in mice

A glass column (1 cm i.d.) was filled with 0.5 g of aminopropyl sorbent and equilibrated with 2 5 mL n- hexane/ethyl acetate 96:4 (v/v) before the sample was added

These approaches rely on cytokine modulation that selectively expands native nTreg populations

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