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10.1016/j.fbio.2025.106007 82 YuanY.LiuY.HeY.ZhangB.ZhaoL.TianS.et al (2022)

Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

Moreover, their anti-glycation and anti-dicarbonyl properties lessen the accumulation of AGEs and other toxic intermediates, consequently protecting peripheral nerves from glycemic damage (Xiao-Fang et al., 2008

However, mice on HFD developed obesity early in the experiment

These pro-inflammatory cytokines circulate in the blood, and have many multifaceted adverse effects on thyroid tissue

Second, the ubiquitinated proteins are extracted and degraded by the ubiquitin-proteasome system, leading to the disruption of multiple MOM [56], subsequently exposing and ubiquitinating the MIM proteins