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When conducting a tail suspension test, reduced immobility time is considered a success when considering antidepressive treatment whereas increased immobility is equated with depressive-like behavior

Waghule T, Gorantla S, Rapalli VK, Shah P, Dubey SK, Saha RN, et al

Aberrant activation of RIPK2 is closely associated with increased expression of signaling molecules in the colonic mucosa of IBD patients, and blocking RIPK2 activation effectively inhibits the development of experimental colitis in mice [463, 464]

(2022) 119:e2213120119

Biochemical investigations showed a normal level of cysteinyl glycine in plasma, an abnormal urinary profile with increased excretion of cysteinyl glycine (4972 mmol/mol of creatinine) and leukotrienes with increased leukotriene D4 and complete absence of LTE4

Woodfield GW, Horan AD, Chen Y, Weigel RJ