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After an initial loading regimen of 1mg three times weekly for two weeks, maintenance therapy is typically 1mg every three months for life in conditions like pernicious anaemia, or every two months if neurological involvement was present

At the same time, the positive results of the feasibility studies on BioChaperone have led us to concentrate our efforts on the development of this platform and enable us to engage in discussions with two large pharmaceutical companies," declares Olivier Soula, CEO and cofounder of Adocia

On other occasions they are used in the short term to reverse and prevent severe deficiencies before the neurological impact caused by a lack of B12 becomes permanent (Wang et al., 2018)

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