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ATC displays enhanced serine and one-carbon metabolism dependency compared to PTC One-carbon metabolism is critical in tumorigenicity against glutamine metabolic changes and chemotherapy in ATC

Iwahashi et al., 2002

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some sources indicate that they may occur in up to 50% of patients, and while advances in surgical techniques helped lower their frequency in recent years, they were still reported to occur in 14-18% of patients, and remain a major complication (Coombes 1999

These stress-induced glial dysfunctions are intimately linked to disturbances in sleep homeostasis, creating a bidirectional feedback loop that exacerbates neural dysfunction