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In addition, increased p53 expression inhibits the expression of the system xc SLC7A11, resulting in reduced uptake of cystine, decreased GSH peroxidase activity, reduced cell antioxidant capacity, and increased sensitivity of cells to ferroptosis (Kang et al., 2019)

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CTAB facilitated the formation of mesoporous structures with defined grain boundaries, while citric acid prevented premature metal ion precipitation, improving particle stability