Ipamorelin activates the ghrelin receptor through a cortisol-sparing pathway enhancing recovery and sleep
Documentation Material specification Purity Test method Form Storage (sealed) Storage (reconstituted) CoA Selected research PMID 9849822 Ipamorelin, the first selective growth hormone secretagogue Eur J Endocrinol, 1998, original characterization, GH release without ACTH or cortisol elevation PMID 10373343 Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats Growth Horm IGF Res, 1999, longitudinal bone growth in adult rats PMID 10496658 Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers Pharm Res, 1999, dose-response GH modeling in healthy male volunteers PMID 11735244 The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult rats Growth Horm IGF Res, 2001, bone-formation rescue under glucocorticoid load PMID 19289567 Efficacy of ipamorelin, a novel ghrelin mimetic, in a rodent model of postoperative ileus J Pharmacol Exp Ther, 2009, intestinal transit and recovery in rats after surgery PMID 25331030 Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients Int J Colorectal Dis, 2014, phase-2 RCT in 114 bowel-resection patients PMID 32801950 Attenuation of Visceral and Somatic Nociception by Ghrelin Mimetics J Exp Pharmacol, 2020, ghrelin-receptor mediated nociception model with ipamorelin Research use only This material is sold strictly for in-vitro research and laboratory use
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