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Regulation of neurotransmitters by the gut microbiota and effects on cognition in neurological disorders

Blood-based biomarkers have proven beneficial in clinical practice in other medical specialties because of the ease of access and low invasiveness of the bio-sampling method ( It is not entirely clear how the peripheral Glu, Gln or the mRNA expression levels of NMDAR NR1 subunit reflect CNS levels

doi: 10.1016/j.cmet.2019.01.014 124 QuallsJESubramanianCRafiWSmithAMBalouzianLDeFreitasAAet al

But factors like pollution, stress, poor diet and aging can deplete your bodys glutathione levels

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Meanwhile, SIRT3 deacetylates metabolic enzymes within the mitochondrial matrix, which is crucial for maintaining metabolic homeostasis [247]