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IR has been found to reduce SLC7A11 expression [47, 48], a component of system x c - , the glutamate/cystine antiporter that allows for cystine import that can fuel reduced glutathione (GSH) synthesis [49]

Although technological maturity continues to improve, cost and data standardization remain bottlenecks to widespread clinical implementation

Moreover, Centella asiatica has historically been utilized in traditional medicine across Asian and African nations for addressing various health concerns, such as diabetes 15

Unlike Actilyse, which requires a 60-minute infusion, Metalyse is administered as a single bolus injection, enabling faster treatment and potentially reducing transfer times for patients requiring additional interventions after initial thrombolysis