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ENVISION, a phase 3 study of safety and efficacy of givosiran, an investigational RNAi therapeutic, in acute hepatic porphyria patients

For other elements, including zinc, iron, copper, and magnesium, emerging associations with AITD have been identified, but the mechanistic understanding remains limited

The regulation of acetate ester production is primarily controlled by the expression of two alcohol acetyl transferases (AATase), Atf1p and Atf2p (Figure 2B) (Yoshimoto et al