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Lead-induced damage to the lining cells of the proximal tubular system results in the formation of nuclear inclusions and ultimately renal glycosuria and aminoaciduria, which are characterized by high levels of sugar and amino acids in the urine, respectively (Kellum et al

211 Throughout the follow-up period, the overall response rate consistently exceeded 80% among patients with PV, while only 10% of these patients experienced grade 3 treatment-related adverse events, suggesting its potential for prolonged clinical use

Other dietary components relevant to GSH synthesis and function, such as selenium, may also be beneficial

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Guidelines for the design and conduct of clinical studies in knee articular cartilage repair:international cartilage repair society recommendations based on current scientific evidence and standards of clinical care