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Injected peptides generally stay active longer than orally or intranasally administered ones due to better absorption and bioavailability

In contrast, its negative correlation with ADO suggests that low ADO levels may help limit tumour-promoting mechanisms, aligning with AZGP1s potential tumour-suppressive role

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Disclosure of interest: Maennle D: nothing to disclose

9 Structural and functional abnormalities in mitochondria have been observed in individuals with IVDD