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AE collected articles and wrote the first draft of manuscript, JWG initiated the study and revised the manuscript and TLW finalized the manuscript

The copper ion is coordinated to the peptide through the nitrogen atoms of the glycine and histidine residues, giving the compound its distinctive blue color in crystalline form

Statements Author contributions SC and VT drafted the manuscript, read and approved the final manuscript, and are responsible for all aspects of the manuscript

Unlike some reusable straws, Softy Straws feature an integrated squeegee cleaner that quickly wipes the inside clean in seconds - no separate brushes or soaking required

The ROS overproduction results in oxidative impairment of lipids, proteins, and DNA (53), where the accumulation of DNA damage induced by ROS may lead to genetic destabilization in the case of cancer, thus facilitating the development of cancer (54)

Pain occurs two or three times more frequently in patients with PD than in individuals of similar age without PD 38 , 39 , 40