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Nature 315:641647 Engelmann H, Novick D, Wallach D (1990) Two tumor necrosis factor-binding proteins purified from human urine

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They are a rich source of soluble factors such as ROS, peptides, cytokines and enzymes that exert antimicrobial activities [257]

Reproducing human and cross-species drug toxicities using a Liver-Chip

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46 showed that a preserved responsiveness to the endothelium-dependent vasodilator acetylcholine, administered intracoronarily, is associated with a significantly lower incidence of cardiovascular events defined as a composite end point, including cardiovascular death, unstable angina, myocardial infarction, coronary revascularization, ischemic stroke and peripheral artery revascularization