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We note that in prior rulemaking, for example, in the CY 2013 PFS final rule, we stated, we further consider[ed] how advanced primary care practices can fit within a fee-for-service model (77 FR 68987), and in the CY 2015 PFS final rule, we stated our commitment to supporting advanced primary care, including the recognition of care management as one of the critical components of primary care that contributes to better health for individuals and reduced expenditure growth (79 FR 67715)

A recurring comment throughout the report was that the in vitro tests included in the newly performed industry studies are not sufficient to perform an evaluation of the CMR (carcinogenic, mutagenic or reprotoxic) properties, since in vivo studies are required to address this issue

They contain a range of additives such as colourings and preservatives, high amounts of sugar, salt and fat, and are often calorie-dense but low in nutrients

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