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In addition, numerous enzymes that involved in thiopurine biotransformation and their variable activities offer a clue for the measurement of serum metabolites which reflect the drug metabolism and distribution and facilitate the determination of the optimum dose of medications for each patient to prevent side effects and toxicities [130] (Fig

Epigenetic effects of short-chain fatty acids from the large intestine on host cells

Cheng G, Salerno JC, Cao Z, Pagano PJ, Lambeth JD (2008) Identification and characterization of VPO1, a new animal heme-containing peroxidase

Environmentally benign synthesis of 4-aminoquinoline-2-ones using recyclable choline hydroxide

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