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In one recent study published in the Nutrition Research and Practice, researchers wrote: Studies have demonstrated that supplementation with vitamin B-complex improves nocturnal leg cramps, suggesting a possible nutritional method for the management of certain types of sleep disorders

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The chemical structure of cyanocobalamin contains the rare mineral cobalt (4.34%), which binds the cyano group and is located in the center of a corrin ring.[5] The commercial manufacturing of the vitamin is done through bacterial fermentation

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Yamakido M, Ishioka S, Hiyama K, Maeda A