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CD4 + T Cell Isolation and Ex Vivo Activation and Expansion Spleens from BDC2.5 animals were harvested and homogenized into single cell suspensions as described above

J Biol Chem 279: 3987239879 Credle JJ, FinerMoore JS, Papa FR, Stroud RM, Walter P (2005) Inaugural article: on the mechanism of sensing unfolded protein in the endoplasmic reticulum

Nuclear factor kappaB (NF-kB) signaling pathway plays a role in COVID-19 progression and selenium is a NF-kB inhibitor

ERO1-, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis

Activation of TLR ligands on astrocytes also leads to the inflammatory response in the CNS (Colombo and Farina, 2016

They were housed under controlled laboratory conditions with a 12h/12 h light/dark cycle, at a constant temperature of 25C 1C and relative humidity of 60% 10%