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Although the reactions catalysed by Gdh2 and Gdh3 are reversible, the Gdh2-catalysed reaction favours the deamination of glutamateits catabolism to -ketoglutarate and ammonium 12

10.1016/j.bbadis.2025.167754 212 WuQ.ZhangD.DaiS.LiuF.ZhangW.ShenT

Although a clear photoactivation role has been established for the photocobilin domain fused to the DGC enzyme domain, the function of the standalone photocobilin photoreceptors is less clear

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This is the same mechanism the body uses naturally during fasting, exercise or stress, AOD-9604 simply amplifies the signal

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