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References Bhattacharya, D

This triggers a cascade of effects: accelerated keratinocyte proliferation, increased desquamation (shedding of the outer layer), and stimulation of collagen synthesis in the dermis

If the benefits of fibrate therapy are indeed mitigated by fibrate-induced betaine deficiency, the use and safety of supplementing patients with betaine would need to be considered (127)

Blood 138 , 11821193 (2021)

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For example, gemcitabine thermosensitive hydrogels or microspheres are used for intraperitoneal perfusion to treat peritoneal metastasis, which can form a drug sustained release reservoir in the peritoneal cavity, prolong local exposure time and reduce systemic toxicity (Xu et al., 2016)