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[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Nakamura Y, Miyata M, Ohba T, Ando T, Hatsushika K, Suenaga F, Shimokawa N, Ohnuma Y, Katoh R, Ogawa H, Nakao A

Moderate exacerbation of COPD after diagnosis was defined as an outpatient visit with ICD-10 J43.X (except J43.0) or J44.X and a prescription for systemic steroids or antibiotics on the same visit

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The concept of ROS for continuous risk can naturally extend to binary risk because the BPRF is still defined as the 5th percentile of the effect size accounting for data uncertainty and between-study heterogeneity

Researchers are still studying the long-term and short-term effects of this substance