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Although these enolases have been shown to facilitate this process both in vivo and in vitro , it would appear as though the plasmin activity facilitated by all three of the major human schistosomes does not rely solely on enolases, as up to 10 plasminogen binding proteins have been identified via western blotting techniques

The synthesis proceeded in two steps

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found that ASCT2 ligands chloroalanine, aminooxetane-3-carboxylate (AOC), and -FBP also inhibit ASCT2-mediated glutamine uptake in human melanoma cells [104]

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