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10.1038/s41598-024-78956-5 16 AnwaarS.IjazD.-E.-S.AnwarT.QureshiH.NazishM.AlrefaeiA

La carnitina un trasportatore degli acidi grassi nei mitocondri cellulari che permette dunque di generare energia

There is no acute diffusion restriction or gradient sequence abnormality

10.4161/cc.10.17.16359 128 LiuF.SongS.YeX.HuangS.HeJ.WangG.et al (2022)

Besides an abnormally short stature, physical symptoms of the syndrome include a prominent forehead, depressed nasal bridge, underdevelopment of the mandible, and truncal obesity [6]

They demonstrated that pretreatment of cultured SOD1 G93A astrocytes with MitoQ was able to reduce the formation of superoxide and peroxynitrite radicals, protect motor neurons against oxidative damage and improve the ability of mitochondria to generate ATP (Cassina et al., G93A mouse model, treatment with MitoQ at the onset of disease also delayed the decline of mitochondrial function in the spinal cord, protected against motor neuron loss and astrogliosis in the spinal cord