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Most studies are based on animal models and in vitro experiments, with small sample sizes that limit statistical power and make the findings susceptible to external objective factors, further affecting their reproducibility and representativeness

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Diethylstilbestrol enhances melanogenesis via cAMP-PKA-mediating up-regulation of tyrosinase and MITF in mouse B16 melanoma cells

In the presence of adequate oxygen, fatty acids are converted by acyl coenzyme A synthetase into acyl coenzyme A, which then undergoes a complex transport process into the mitochondria

10.1073/pnas.2115912119 76 MabuchiY.YamotoM.MinamiS.UmesakiN