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Given the overlap between metabolic syndrome and non-alcoholic fatty liver disease (NAFLD), it is possible that eicosanoids may also predict CVD events in patients with NAFLD, though this has not yet been elucidated

Management of neuroleptic malignant syndrome requires immediate discontinuation of the offending antipsychotic and aggressive supportive care, including rapid cooling and intravenous fluids to maintain renal perfusion

GSH-conjugate export carriers (known variably as GS-X pumps or multispecific organic anion transporters) are involved, and this export function is undertaken, in large part, by the ABC transporters MRP1 and MRP2 (Cole and Deeley, 2006

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In summary, ROS contribute to various aspects of necroptosis, including the initiation of signaling cascades, amplification of key protein activity, modulation of energy metabolism, activation of MLKL, and the establishment of a feedback loop