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Sarcoma 2014 , 498682 (2014)

Methylome analyses have revealed changes in MSC global DNA methylation landscape during aging and senescence wherein multipotential and proliferation are being compromised [96, 97], suggesting that DNA methylation and demethylation are critical processes to govern the gene expression that contributes to MSC behavior

Siwak, J

Emerging research across various diseases, including cancers and cardiovascular diseases, has revealed that certain miRNAs can be involved in the same biological pathways either as effectors or regulators (201)

large-scale cohort studies have shown that regular participation in activities such as swimming, racquet sports, and aerobics is associated with a 36%56% reduction in all-cause and cardiovascular mortalities compared to sedentary behavior (105)