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Recently, an increasing number of studies have demonstrated the important regulatory role played by epigenetic mechanisms, especially DNA, RNA, and protein methylation, in ferroptosis

We hypothesize that the selenium-iodine-induced oxidative eustress acts as a signal that shunts metabolic precursors away from the phenylpropanoid pathway (which produces eugenol) and toward the methylerythritol phosphate pathway, which leads to linalool synthesis

It's creating a ton of energy, but it's also filling the room with toxic, suffocating exhaust (oxidative stress)

Additionally, studies show that GPX4 inactivation induces hippocampal neuron death, while alpha-lipoic acid protects neurons by regulating GPX4 expression (Zhang YH

Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells

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