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Our data demonstrate that ABCB7 accommodates two stacked CoPP molecules within the central cavity, in a nearly vertical orientation relative to the membrane (Fig

Fatty liver disease, also known as hepatic steatosis, is a condition characterized by the accumulation of excess fat in liver cells

ABTS was oxidized to green ABTS + under the action of appropriate oxidants, and the production of ABTS + could be inhibited in the presence of antioxidants

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These detoxifying mechanisms may be phase I detoxifying enzymes such as aldehyde dehydrogenases, alcohol dehydrogenases, aldo-keto reductase, and other enzymes ( The tumor microenvironment is enriched with ROS that have multifaceted roles in cancer cell proliferation, apoptosis, angiogenesis, and metastasis ( GSTA4 cells regardless of increased ROS, implying that inactivation of GSTA4 mildly increases ROS that might promote proliferation