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Studies have shown that improper consumption of these foods could cause damage to the kidney, liver, and heart, and even death, e.g., gardenoside in Zhizi ( Gardenia jasminoides J

Additionally, key proteins involved in ubiquitination process were secreted with itaconation, such as Ubiquitin carboxyl-terminal hydrolase 5 (USP5), USP14, USP19, USP39 and Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X), potentially mediating signaling between itaconate and protein degradation (Fig

The specific analysis of CSF samples from amnestic MCI and AD subjects identified the early carbonylation of extracellular chaperones, suggesting that dysfunction of these pathways is initiated many years before severe dementia is diagnosed and might represent a reliable biomarker for pathology onset and progression (311, 318,319)

Graphical Abstract Similar content being viewed by others Introduction Diquat (DQ), 1,1'-ethylene-2,2'-bipyridylium, is a commonly used organic heterocyclic herbicide for crop protection and weed control in aquatic environments (Li et al

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Using comedogenic products can block skin pores, irritate skin & cause pimples