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doi: 10.1016/S0167-4781(00)00026-9 52 LippaA

Nutrient regulation of mTORC1 at a glance

Zhang FD

KOG classes represent high level conserved functions of orthologous genes across eukaryotic taxa, thereby facilitating the comparison of functional characteristics of transcriptomic responses across the tree of life 63

For example, GHSR are localised in the pituitary where ghrelin stimulates growth hormone secretion (10, 11)

Studies show that QSM-derived iron levels correlate significantly and negatively with cognitive function in AD patients, confirming the role of iron dysregulation in the disease mechanism (11, 179)