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The gut microbiota metabolite propionate ameliorates intestinal epithelial barrier dysfunction-mediated Parkinsons disease via the AKT signaling pathway

The quantification of the total amounts of succinate and malate was performed employing a Bruker Advance UHPLC system coupled to ESI-MS/MS (EVOQTQMS) for chromatographic separation, fragmentation and quantification as described in Larsen ( Larsen, T.M

Multiple analytical techniques utilizing spectrophotometric and fluorometric detection have emerged for TAC quantification in biological specimens, with each methodology employing unique chemical mechanisms to evaluate integrated antioxidative responses

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[DOI] [PubMed] [Google Scholar] 35.Brodersen H.P., Holtkamp W., Larbig D., Beckers B., Thiery J., Lautenschlager J., Probst H.J., Ropertz S., Yavari A

Potential insulin sensitivity changes While no direct evidence suggests a negative effect on blood sugar, some peptides may affect insulin signaling over time