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Deficiency of this micro-element also leads to activation of NADPH oxidase, ROS and reactive nitrogen species (Lee et al., 2021)

The likelihood of experiencing migraines increases if there is a familial pattern of the disorder, and the presence of other medical conditions, such as mood or sleep disturbances, can heighten ones susceptibility

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10.1183/09031936.04.00002404 26 DaiX.ZhangX.ChenW.ChenY.ZhangQ.MoS.et al (2021)

Although the association was not significant within the autism cohort, the clustering of the autism cases in the bottom right quadrant with significantly higher 8-oxo-dG levels and lower GSH/GSSG is apparent