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This results in the activation of mast cells and the release of inflammatory mediators, including histamine, leukotrienes and others, which can manifest as pruritus, urticaria, angioedema, bronchospasm, vomiting and hypotension

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However, there can be no guarantee that the estimates contained in such forward-looking statements will be achieved, as such estimates are subject to numerous risks including those set forth in the Risk Factors section of the universal registration document that was filed with the French Autorit des marchs financiers on April 29, 2025, as updated in the Companys 2025 Half-year financial statements, published on September 25, 2025, both available at www.adocia.com