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Praptiwi et al., 2021

Rahmati M, Yazdanparast M, Jahanshahi K, Zakeri M

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Vasorelaxation at least 60% by 3 M ACh in rings pre-contracted with 3 M PE was considered endothelium intact

Contraindications Do not use DSIP if you: Are pregnant or breastfeeding (insufficient safety data) Have sleep apnea or other breathing-related sleep disorders (sedation risk) Take prescription sedatives or sleep medications Have a history of severe reactions to injected peptides Are under 18 years old If you have any chronic medical condition or take regular medications, consult a healthcare provider familiar with peptide therapies before starting DSIP

For example, the American Academy of Radiology does not recommend full-body MRIs because, according to a 2023 statement, there is no documented evidence that total body screening is cost-efficient or effective in prolonging life